ANTIBIOTIC RESISTANCE: CHALLENGES, MECHANISMS, AND GLOBAL SOLUTIONS FOR COMBATING THE CRISIS

Authors

  • Resti tito villarino cebu technological university, moalboal campus, cebu, philippines national research council of the philippines, manila, philippines. Author

DOI:

https://doi.org/10.71465/bhsr39

Keywords:

Antibiotic resistance, antimicrobial resistance, multidrug-resistant pathogens, healthcare, agricultural misuse, antimicrobial stewardship, novel antibiotics, global health, resistance mechanisms, alternative therapies, policy recommendations

Abstract

Antibiotic resistance (ABR) is a significant global health threat that threatens the efficacy of current antimicrobial therapies. The increasing prevalence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) pathogens has necessitated immediate action to address the crisis. This paper provides an in-depth analysis of the challenges and potential solutions to combat antibiotic resistance. It highlights the mechanisms of resistance, the role of overuse and misuse of antibiotics in clinical and agricultural settings, and the socio-economic implications of ABR. Furthermore, the paper discusses novel approaches, including the development of new antibiotics, alternative therapies, and antimicrobial stewardship programs, aimed at mitigating the spread of resistant pathogens. The article concludes with policy recommendations for enhancing global efforts to tackle this growing concern.

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Published

2023-12-31